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We currently have a number of appeals funding groundbreaking research to help the countless families and children affected by premature birth and pregnancy complications, disabilities, and rare and devastating diseases. Find out more about our current research appeals on our main website.

Our most recent appeal aims to raise over £1m to fund research to better understand how COVID-19 affects children.

Give all important hope

Mitochondrial DNA depletion syndrome (MDDS) is a rare and cruel genetic disease that takes children's lives. In its most severe form, it starts in early infancy and has devastating symptoms, causing a variety of neurological problems and progressive liver failure – and tragically, as there is currently no cure, many children will lose their lives at a very young age.

We are funding a cutting-edge research project that could help produce a cure for MDDS, giving all important hope to families that, in the future, lives could be saved.

Cerebral palsy research

Tom was just a baby when he was diagnosed with quadriplegic cerebral palsy – a severe physical disability.

Now 6, his disability has affected all aspects of his life. He uses a wheelchair and everyday activities such as eating and playing with toys are challenging. He has also developed epilepsy.

Action is dedicated to helping children like Tom, which is why we’re funding several research projects into cerebral palsy.

Fighting childhood cancers

Joey was just four years old when we was diagnosed with brain cancer. He battled a gruelling year of surgery, chemotherapy and radiotherapy.

Joey is now ten and thankfully symptom free, but we know not every story is the same as Joey's.

That's why Action is funding vital research into childhood cancers to help more children diagnosed with cancer.

Research into cystic fibrosis

Every week in the UK, around four people – many of them babies and children – are diagnosed with the cystic fibrosis. Making it the UK's commonest life-threatening inherited disease that can make it hard for children to breathe and for their bodies to digest food.

Currently there is no cure for cystic fibrosis and although there are treatments to ease symptoms these can be time-consuming and gruelling.

Action is determined to help which is why we're currently funding research projects that aim to help improve the quality of life of babies and children with cystic fibrosis.

Stopping scarlet fever

After decades of decline, scarlet fever infections hit a 50-year high in England in 2016. Thanks to modern antibiotics, it's usually not serious, but the strep A bacteria that cause it can have a darker side.

That's why we're funding research at Imperial College London that hopes to reduce the spread of infection to help lower the risk of more serious life-threatening diseases. The research will also help guide public health strategy on scarlet fever.

Help fight neuroblastoma

Every year in the UK, around 100 children are diagnosed with neuroblastoma - a rare and devastating form of childhood cancer. Most children with low-risk neuroblastoma will be cured, but the outlook is less certain for children with high-risk neuroblastoma. These children need extremely intensive treatment that can last for years and despite the intensity of treatment, only 40 to 50 per cent survive for five or more years.

We're funding a potentially groundbreaking research project that aims to develop a new treatment to fight this disease, that has fewer side-effects and provides lifelong protection, saving more children's lives.