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We currently have six exciting appeals to help save and change children's lives. Firstly we've have two appeals to help tackle premature birth and pregnancy complications. We've also recently launched an appeal to help fund an exciting and potentially groundbreaking research in the area of premature birth that hopes to identify women in early pregnancy who are at risk of premature birth. And lastly we have appeals funding potentially life-changing research projects into developing new treatments and cures for devastating rare diseases such as BPAN, neuroblastoma and mithochondrial DNA depletion syndrome (MDDS).

We have over 65 research projects live across the UK - searching for answers and offering hope for children and their families.

You can find out more about just some of these areas of our work and research projects that we're currently funding below where there are opportunities to support our wider work.

Join our fight for little lives.

Give all important hope

Mitochondrial DNA depletion syndrome (MDDS) is a rare and cruel genetic disease that takes children's lives. In its most severe form, it starts in early infancy and has devastating symptoms, causing a variety of neurological problems and progressive liver failure – and tragically, as there is currently no cure, many children will lose their lives at a very young age.

We are funding a cutting-edge research project that could help produce a cure for MDDS, giving all important hope to families that, in the future, lives could be saved.

Help STOP babies being born too soon

Premature birth is the biggest cause of newborn death in the UK, and for those babies who do survive they can grow up with life-changing conditions – including cerebral palsy, learning difficulties, blindness and hearing loss. We know through medical research we can save children's lives. But we can't do this alone.

We urgently need your help to raise £15,000 towards funding a vital piece of research, led by Professor Rachel Tribe at King's College London, to develop a new screening test to identify women at risk of premature birth. If successful, this would enable more effective clinical care to be taken to help prevent these women from giving birth too soon, and reduce the number of babies born prematurely.

Help fight neuroblastoma

Every year in the UK, around 100 children are diagnosed with neuroblastoma - a rare and devastating form of childhood cancer. Most children with low-risk neuroblastoma will be cured, but the outlook is less certain for children with high-risk neuroblastoma. These children need extremely intensive treatment that can last for years and despite the intensity of treatment, only 40 to 50 per cent survive for five or more years.

We're funding a potentially groundbreaking research project that aims to develop a new treatment to fight this disease, that has fewer side-effects and provides lifelong protection, saving more children's lives.

Help Stop Premature Birth

No parent expects their baby to be born prematurely or for their little one to spend days, weeks or even months in intensive care. But sadly this is the reality for more and more parents.

Each year, around 61,000 babies in the UK are born preterm and sadly more than 1,000 babies die as a result of being born too soon.

Action Medical Research want to help stop premature birth. We are funding a potentially ground-breaking research project which hopes to delay early labour, save more little lives and save more families the heartache of losing a child. But we urgently need your help to fund this vital project.

Saving Tiny Lives campaign

Premature birth and its complications are the leading cause of death among children under five years of age across the world. In the UK alone, around 61,000 babies are born prematurely each year and tragically more than 1,000 of these babies die.

We've launched this campaign because Action believe that only by investing in research can the devastation caused by premature birth and pregnancy complications be stopped.

Please make your pledge to save tiny lives today. This is a huge and exciting opportunity – to be a part of our campaign to fund potentially groundbreaking medical research that could go on to benefit millions.

Lily laughing

Vital research into BPAN

Lily is living with BPAN - a rare and devastating neurological disease for which there is no cure.

This disease strikes young children, causing them to develop slowly and to miss key developmental milestones. It leads to seizures, muscle problems, symptoms of Parkinson’s, dementia and eventually early death.

We want to work towards a cure and have promised to fund a potentially groundbreaking research study – but we need your help.

Cerebral palsy research

Tom was just a baby when he was diagnosed with quadriplegic cerebral palsy – a severe physical disability.

Now 6, his disability has affected all aspects of his life. He uses a wheelchair and everyday activities such as eating and playing with toys are challenging. He has also developed epilepsy.

Action is dedicated to helping children like Tom, which is why we’re funding several research projects into cerebral palsy.

Fighting childhood cancers

Joey was just four years old when we was diagnosed with brain cancer. He battled a gruelling year of surgery, chemotherapy and radiotherapy.

Joey is now ten and thankfully symptom free, but we know not every story is the same as Joey's.

That's why Action is funding vital research into childhood cancers to help more children diagnosed with cancer.

Research into cystic fibrosis

Every week in the UK, around four people – many of them babies and children – are diagnosed with the cystic fibrosis. Making it the UK's commonest life-threatening inherited disease that can make it hard for children to breathe and for their bodies to digest food.

Currently there is no cure for cystic fibrosis and although there are treatments to ease symptoms these can be time-consuming and gruelling.

Action is determined to help which is why we're currently funding research projects that aim to help improve the quality of life of babies and children with cystic fibrosis.

Stopping scarlet fever

After decades of decline, scarlet fever infections hit a 50-year high in England in 2016. Thanks to modern antibiotics, it's usually not serious, but the strep A bacteria that cause it can have a darker side.

That's why we're funding research at Imperial College London that hopes to reduce the spread of infection to help lower the risk of more serious life-threatening diseases. The research will also help guide public health strategy on scarlet fever.